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These bioreactor flasks are viable in vitro alternatives to using mouse ascites, standard cell culture, or tissue culture products. Bioreactors utilize innovative membrane technology to separate the cell cultivation area from the media chamber. Cells and cellular-secreted products with a MWCO over 10kD are retained between two non-cytotoxic membranes. The upper semi-permeable membrane allows continuous nutrient diffusion and waste elimination. The lower membrane provides direct oxygenation and ensures optimum gas exchange. Separate ports give access to either media or cell cultivation chamber allowing easy change of expended medium without interference of cell growth, function, or gas exchange.
Designed for stem cell expansion, primary cell culture, and antibody production. Allows production of up to 2 x 108 cells per cell compartment. The 5 mL cultivation chamber is ideal for all tissues where cell density is important. A 350 mL media compartment has vertical and horizontal volume markings from 50-350mL. Produces about 27mg/month of antibody.
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