Cole-Parmer Essentials Adhere Bioreactor Flask for Adherent Cells, Dual Membrane, 1000 mL (33.8 oz), 3 Pk

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Cole-Parmer Essentials Item # EW-24406-55
Cell culture bioreactor flasks ideal for monoclonal antibodies and expressed recombinant cellular protein production
  • Generates more highly concentrated supernatants than roller bottles or tissue culture flasks with the same cell type
  • Low-cost bioreactor for the production of expressed biomolecules
  • Reduces waste - replaces between 10 to 20 normal culture flasks
  • Culture cells for longer - nutrients not depleted
  • Saves incubator space
  • Gamma irradiation sterilized and pressure tested

PRODUCT OPTIONS

$1,096.00USD / Case of 3
Traceable Three-Channel Timer
$73.50USD / Each

SPECS & DESCRIPTION

Specifications & Description

  • MaterialPolystyrene housing, molded silicone gas transfer bottom, and cellulose membrane
  • SterileYes
  • Capacity (mL)1000
  • DescriptionAdhere Bioreactor Flask for Adherent Cells, Dual Membrane, 1000 mL (33.8 oz), 3 Pk

Key Features

  • Generates more highly concentrated supernatants than roller bottles or tissue culture flasks with the same cell type
  • Low-cost bioreactor for the production of expressed biomolecules
  • Reduces waste - replaces between 10 to 20 normal culture flasks
  • Culture cells for longer - nutrients not depleted
  • Saves incubator space
  • Gamma irradiation sterilized and pressure tested

More About this Item

These bioreactor flasks are viable in vitro alternatives to using mouse ascites, standard cell culture, or tissue culture products. Bioreactors utilize innovative membrane technology to separate the cell cultivation area from the media chamber. Cells and cellular-secreted products with a MWCO over 10kD are retained between two non-cytotoxic membranes. The upper semi-permeable membrane allows continuous nutrient diffusion and waste elimination. The lower membrane provides direct oxygenation and ensures optimum gas exchange. Separate ports give access to either media or cell cultivation chamber allowing easy change of expended medium without interference of cell growth, function, or gas exchange.

Developed for the expression of biomolecules in anchorage dependent cell lines. The observed product concentrations in the cell compartment are in the range of 1-5 mg/mL and are often several hundred times higher than what is obtained in either roller bottles or tissue culture flasks with the same cell type. Ideal for use with CHO, BHK, HEp-2 or any other adherent cell line. The flask is reusable and greatly reduces the downstream processing cost of concentration and purification. Serum usage is also reduced as a result of the compartmentalized chambers in the flask. The result is a low-cost bioreactor for the production of expressed biomolecules.

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