power supply, power cord, ethernet cable (1).
The picoSpin-45 proton NMR spectrometer is a true breakthrough in chemical instrumentation. Now you can afford a dedicated NMR spectrometer for your research, for your process, or for your classroom. Liquid samples are simply injected into an internal capillary via front-panel fittings, and only 20 microliters of sample fluid is needed to obtain a spectrum.
A highly stable temperature-controlled permanent magnet ensures easy maintenance-free operation without the need for liquid cryogens. The unit occupies a small fraction of the space of a conventional NMR spectrometer and it does not require specialized knowledge or training for operation. NMR data is generated in the industry-standard JCAMP-DX format for compatibility with standard NMR data analysis packages.
The unit's fluid capillary is contained within a cartridge and is easily user replaceable in the event it becomes blocked or contaminated.
In order to know if you have 1/16-inch or 1/32-inch fittings on your picoSpin, look at the inlet fitting of your picoSpin-45. If you see two stainless hex nuts, you have 1/32-inch fittings. If you see one stainless hex nut, you have 1/16-inch fittings.
In general, capillary cartridges shipped before January 2013 have 1/32-inch fittings. Capillary cartridges shipped after January 2013 generally will have 1/16-inch fittings. Please contact our applications specialists if you need further assistance.
Order 83090-01 for a high temperature unit, or 83090-02 for a specialized fluorine model option.
Contact our application specialists for more details on any picoSpin-45 model.
Reviewed by 2 customers
Displaying reviews 1-2
Comments about picoSpin 45L Benchtop NMR Spectrometer; 115/230 VAC:
The person I worked with at coleparmer to set up the NMR was travelling and gave delayed responses with incomplete answers to questions about software setup. Thus the update process was clunky and delayed by extra steps that weren't explained completely. So was the installation and linkup of the Mnova software.
I was surprised by the apparent lack of communication between the two companies. For one example (there have been several), Mnova was unaware that I had registered the software for the one year licence that comes with the instrument (after finally getting the licence set up) and asked me to send them a screenshot of the licence manager in their own software to confirm the registration. This is not a big deal, but there have been quite a few such "surprise" extra steps that roughened the experience and chews up time.
So in summary, its very good hardware, and it will do what you expect a really good 45 mHz 1D proton NMR to do. I'm certain that when the glitchy customer service and software set up is worked out, the process will be a productive experience for future customers.
Comments about picoSpin 45L Benchtop NMR Spectrometer; 115/230 VAC:
We measure a variety of solvents in our QA lab. This thing paid for itself in only a few weeks. We can now run samples in a fraction of the time it took waiting on the high-field machine. Everything about it is fast and easy: setup, connection, running samples, recording data. I bet my daughter could run this.
Do you have questions about this product?
Get answers from real customers and in-house experts with AnswerBox.
Q:did it provide presat/watergate suquences to suppress unnecessary peak?
A:WATERGATE will require multi-pulse sequences e.g. 3α–τ–9α–τ–19α–τ–19α–τ–9α–τ–3α. Our instrument is not capable of generating either pulsed gradients or pulsed field gradients.
Q:How long does it take to autoshim the instrument and often should you shim it.
A:Shimming should typically be performed once a day. One will not need to shim from sample to sample. The longer the instrument stays 'at temperature' the less shimming one needs to do (but still, a daily check is prudent). The automatic shimming script typically takes about 15-25 minutes depending on the settings used.
Q:I would like to know if this instrument would be useful for the analysis of humic substances i.e. humic and fulvic acids? These are complex organic acids obtained from lignite, leonardite and peats and can range in molecular weight from less than 1000 to greater than 300,000 Da. Similar to but more complex than lignin.
A:The limitation is not so much molecular weight but viscosity and sample concentration. One can inject high molecular weight samples, like some large amino-acids, so long as the viscosity isn't too high. Spectra have been measured for dissolved solid samples with molecular weight as high as 800 and 1000 g/mol. With this being said, there will be couple of issues that we will run into with regards to macromolecules such as humic acids. 1) What one may observe in a 45MHz spectrum are fairly broad signals; structure elucidating will not be highly resolved. 2) Proper concentrations (>1M) with this molecule will be almost unachievable at molecular weights exceeding the lower limit mentioned. Please contact our technical support department for further discussion regarding this topic.
Q:How is the capillary tube cleaned out in between samples?
A:Flushing between samples is not required, as each sample will push the last sample residuals out of the way. If one wishes to, one can run samples in duplicate to mitigate any concern with cross-contamination/reactivity. Samples can be flushed with a compatible solvent.
Q:Is the Mnova software use to collect the data or to analyze the data or both?
A:There is a distinction which needs to be made concerning the software needed for the picoSpin-45 spectrometer. All the software necessary to operate the spectrometer, from temperature control to data acquisition, is embedded in the instrument electronics and is developed by picoSpin LLC - there is no license necessary here as it is part of the unit. The Mestrelab MNova software is post-acquisition processing software for which we include a 1-year license in order to provide a full turnkey experience of the picoSpin-45 spectrometer. This is an important incentive for customers who don't already have NMR processing software at their disposal.
Q:What is the field strength in Tesla
A:The field strength at 45 MHz proton Larmor frequency is 1 Tesla.
Q:Can I record 31P NMR in this instrument?
A:This product is primarily for 1H NMR applications, but with some modification can also run 19F. Please contact our technical application specialists for additional assistance (contact information can be found in the "contact us" section on the web page).
Q:Does it have run an automated shimming program or it has to be shimmed manually? Can it be switched off after use or it has to remain on like the conventional NMR instruments?
A:We have an autoShim script for automatic shimming of the 3 linear gradient and 5 quadratic shim coils. One can shim the linear coils separately from the quadratic ones, or vice versa, and they can be shimmed all together. One can, if sufficiently motivated and inclined to do so, manually adjust the individual shim currents.
Q:What kind of experiments can be performed? Can one perform COSY, TOCSY, NOESY/ROESY experiments? If yes what is the experiment time? Can other nuclei viz 19F be observed on this instrument?
A:Right now a one pulse script is available. Soon we will be releasing a T1 inversion recovery script and pulse calibration script; multi-pulse sequences would then be a natural extension. We'll be looking into the possibility of T2 spin echo and COSY experiments - these latter experiments require development. Beyond these experiments there are no immediate plans. As for other nuclei we can also observe 19F.
Q:Can you use it for continuous flow analysis?
A:Yes, indeed. First of all the picoSpin-45 spectrometer is controlled by a web server embedded in the instrument, which can be accessed by any computer on the LAN to which it is connected. Integration of the spectrometer into a process line would require engineering the connection between process flow and the syringe-port inlet bulkhead connector on the spectrometer. For example, one could include a sampling pump which draws a small volume and redirects this flow into the spectrometer for analysis - this would have to be a stopflow design where the sample is essentially static during the timescale of the NMR measurement.
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