Excellent choice when a shorter retention time is required
Similar to C18 but with reduced hydrophobicity—excellent for lipids and steroids
Use for method development from pH 2 to 10—works with acids, bases, and neutrals
Based on ultrapure silica
Excellent peak shapes
Fully scalable from UHPLC to prep
The C8 columns have less dense stationary phase providing low retention time when compared to C18. Because there are less carbon atoms, the analytes elute faster in the C8 columns. The reduced hydrophobicity causes faster retention of nonpolar compounds making them move down the column rapidly. Based on ultrapure silica, the C8 performs well in a wide range of pH.
Columns come in 316L stainless steel (SS) tubing hardware. A SS female end fitting with a SS and PEEK frit system keeps the stationary phase in place and packed bed from disturbance. The SS end fitting accepts a male 10-32 threaded nut with standard 1/16" OD tubing.
Use the guard cartridges to maintain chromatographic integrity. They ensure erroneous materials are kept out of the more important and expensive analytical columns, leading to more accurate results. Simply match the sizes to select the correct guard cartridge for your column; guard cartridge holder 16470-89 is required to use the guard cartridges. In-line filters are available for your UPHLC and HPLC columns—order separately.
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