Cole-Parmer® Cyano HPLC & UHPLC Columns and Accessories

Excellent for separating polar compounds
  • Cyano functionality—decreased retention for hydrophobic compounds when comparing to a C18
  • Can be used for both reverse-phase or normal-phase separation
  • Excellent peak shape and retention of strongly basic analytes
  • Rapid elution of hydrophobic analytes
The cyano columns are less retentive than C18 and C8 in reverse-phase applications. Applications include the retention and separation of strongly basic analytes and fast elution of hydrophobic molecules. Use in normal phase systems to retain and separate polar analyte compounds. It is ideal for the separation of aromatic alcohols, pesticides, and broad ranges of pharmaceuticals, including steroids and analgesics.

Columns come in 316L stainless steel (SS) tubing hardware. A SS female end fitting with a SS and PEEK frit system keeps the stationary phase in place and packed bed from disturbance. The SS end fitting accepts a male 10-32 threaded nut with standard 1/16" OD tubing.

Use the guard cartridges to maintain chromatographic integrity. They ensure erroneous materials are kept out of the more important and expensive analytical columns, leading to more accurate results. Simply match the sizes to select the correct guard cartridge for your column; guard cartridge holder 16470-89 is required to use the guard cartridges. In-line filters are available for your UPHLC and HPLC columns—order separately.
$338.00 - $664.00USD / Each

21 variations of this product are available.

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Column Inside Diameter (ID) (mm) Column Particle Size (µm) Description
Availability Pricing
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4.6 5 Cyano HPLC Column, 5 µm, 250 mm L x 4.6 mm ID; 1/EA
$600.00USD / Each
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4.6 5 Cyano HPLC Column, 5 µm, 150 mm L x 4.6 mm ID; 1/EA
$578.00USD / Each
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4.6 5 Cyano HPLC Column, 5 µm, 100 mm L x 4.6 mm ID; 1/EA
$567.00USD / Each
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2.1 5 Cyano HPLC Column, 5 µm, 50 mm L x 2.1 mm ID; 1/EA
$513.00USD / Each
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4.6 3 Cyano HPLC Column, 3 µm, 150 mm L x 4.6 mm ID; 1/EA
$632.00USD / Each
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4.6 3 Cyano HPLC Column, 3 µm, 100 mm L x 4.6 mm ID; 1/EA
$621.00USD / Each
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2.1 3 Cyano HPLC Column, 3 µm, 150 mm L x 2.1 mm ID; 1/EA
$589.00USD / Each
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2.1 3 Cyano HPLC Column, 3 µm, 100 mm L x 2.1 mm ID; 1/EA
$578.00USD / Each
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2.1 3 Cyano HPLC Column, 3 µm, 50 mm L x 2.1 mm ID; 1/EA
$567.00USD / Each
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4.6 1.7 Cyano UHPLC Column, 1.7 µm, 50 mm L x 4.6 mm ID; 1/EA
$664.00USD / Each
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2.1 1.7 Cyano UHPLC Column, 1.7 µm, 150 mm L x 2.1 mm ID; 1/EA
$631.00USD / Each
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2.1 1.7 Cyano UHPLC Column, 1.7 µm, 100 mm L x 2.1 mm ID; 1/EA
$621.00USD / Each
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2.1 1.7 Cyano UHPLC Column, 1.7 µm, 50 mm L x 2.1 mm ID; 1/EA
$610.00USD / Each
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4.6 5 Cyano Guard Cartridges, 5 µm, 10 mm L x 4.6 mm ID; 2/PK
$338.00USD / Pkg of 2
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4.6 5 Cyano Guard Cartridges, 5 µm, 10 mm L x 4.6 mm ID; 4/PK
$608.00USD / Pkg of 4
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2.1 5 Cyano Guard Cartridges, 5 µm, 10 mm L x 2.1 mm ID; 2/PK
$338.00USD / Pkg of 2
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2.1 5 Cyano Guard Cartridges, 5 µm, 10 mm L x 2.1 mm ID; 4/PK
$608.00USD / Pkg of 4
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4.6 3 Cyano Guard Cartridges, 3 µm, 10 mm L x 4.6 mm ID; 2/PK
$338.00USD / Pkg of 2
COMPARE
4.6 3 Cyano Guard Cartridges, 3 µm, 10 mm L x 4.6 mm ID; 4/PK
$608.00USD / Pkg of 4
COMPARE
2.1 3 Cyano Guard Cartridges, 3 µm, 10 mm L x 2.1 mm ID; 2/PK
$338.00USD / Pkg of 2
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