Cole-Parmer® Diol HPLC & UHPLC Columns and Accessories

Designed to aid in the separation and retention of very polar analytes
  • Use to increase sensitivity in MS analysis
  • Provides alternate selectivity to that achieved with reversed phase chemistries
  • Can be used for HILIC or normal phase mode
  • Reduced extraction and dry down times
These hydrophilic chromatographic columns have diol groups bonded to a silica matrix to separate polar to highly polar compounds that have poor retention on reversed-phase columns. Obtain good retention with eluents containing high concentrations of organic solvents. It has a good separation effect on polar compounds, and it is also used for separation of peptides, proteins, and polar drug molecules.

Columns come in 316L stainless steel (SS) tubing hardware. A SS female end fitting with a SS and PEEK frit system keeps the stationary phase in place and packed bed from disturbance. The SS end fitting accepts a male 10-32 threaded nut with standard 1/16" OD tubing.

Use the guard cartridges to maintain chromatographic integrity. They ensure erroneous materials are kept out of the more important and expensive analytical columns, leading to more accurate results. Simply match the sizes to select the correct guard cartridge for your column; guard cartridge holder 16470-89 is required to use the guard cartridges. In-line filters are available for your UPHLC and HPLC columns—order separately.
$338.00 - $664.00USD / Each

21 variations of this product are available.

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Column Inside Diameter (ID) (mm) Column Particle Size (µm) Description
Availability Pricing
COMPARE
4.6 5 Diol HPLC Column, 5 µm, 250 mm L x 4.6 mm ID; 1/EA
$600.00USD / Each
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4.6 5 Diol HPLC Column, 5 µm, 150 mm L x 4.6 mm ID; 1/EA
$578.00USD / Each
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4.6 5 Diol HPLC Column, 5 µm, 100 mm L x 4.6 mm ID; 1/EA
$567.00USD / Each
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2.1 5 Diol HPLC Column, 5 µm, 50 mm L x 2.1 mm ID; 1/EA
$513.00USD / Each
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4.6 3 Diol HPLC Column, 3 µm, 150 mm L x 4.6 mm ID; 1/EA
$632.00USD / Each
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4.6 3 Diol HPLC Column, 3 µm, 100 mm L x 4.6 mm ID; 1/EA
$621.00USD / Each
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2.1 3 Diol HPLC Column, 3 µm, 150 mm L x 2.1 mm ID; 1/EA
$589.00USD / Each
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2.1 3 Diol HPLC Column, 3 µm, 100 mm L x 2.1 mm ID; 1/EA
$578.00USD / Each
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2.1 3 Diol HPLC Column, 3 µm, 50 mm L x 2.1 mm ID; 1/EA
$567.00USD / Each
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4.6 1.7 Diol UHPLC Column, 1.7 µm, 50 mm L x 4.6 mm ID; 1/EA
$664.00USD / Each
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2.1 1.7 Diol UHPLC Column, 1.7 µm, 150 mm L x 2.1 mm ID; 1/EA
$631.00USD / Each
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2.1 1.7 Diol UHPLC Column, 1.7 µm, 100 mm L x 2.1 mm ID; 1/EA
$621.00USD / Each
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2.1 1.7 Diol UHPLC Column, 1.7 µm, 50 mm L x 2.1 mm ID; 1/EA
$610.00USD / Each
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4.6 5 Diol Guard Cartridges, 5 µm, 10 mm L x 4.6 mm ID; 2/PK
$338.00USD / Pkg of 2
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4.6 5 Diol Guard Cartridges, 5 µm, 10 mm L x 4.6 mm ID; 4/PK
$608.00USD / Pkg of 4
COMPARE
2.1 5 Diol Guard Cartridges, 5 µm, 10 mm L x 2.1 mm ID; 2/PK
$338.00USD / Pkg of 2
COMPARE
2.1 5 Diol Guard Cartridges, 5 µm, 10 mm L x 2.1 mm ID; 4/PK
$608.00USD / Pkg of 4
COMPARE
4.6 3 Diol Guard Cartridges, 3 µm, 10 mm L x 4.6 mm ID; 2/PK
$338.00USD / Pkg of 2
COMPARE
4.6 3 Diol Guard Cartridges, 3 µm, 10 mm L x 4.6 mm ID; 4/PK
$608.00USD / Pkg of 4
COMPARE
2.1 3 Diol Guard Cartridges, 3 µm, 10 mm L x 2.1 mm ID; 2/PK
$338.00USD / Pkg of 2
Showing 1 - 20 of 21

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