Cole-Parmer® Essentials Cell-Line Bioreactor Flasks

Ideal for monoclonal antibodies and expressed recombinant cellular protein production

• Constructed with a polystyrene housing and molded silicone gas transfer bottom
• Features a 10,000 MWCO regenerated cellulose semi-permeable membrane and 0.2µm bottom vent membrane barrier
• Gamma irradiation sterilized and pressure tested

These bioreactor flasks are viable in vitro alternatives to using mouse ascites, standard cell culture, or tissue culture products. Bioreactors utilize innovative membrane technology to separate the cell cultivation area from the media chamber. Cells and cellular-secreted products with a MWCO over 10kD are retained between two non-cytotoxic membranes. The upper semi-permeable membrane allows continuous nutrient diffusion and waste elimination. The lower membrane provides direct oxygenation and ensures optimum gas exchange. Separate ports give access to either media or cell cultivation chamber allowing easy change of expended medium without interference of cell growth, function, or gas exchange.