Cole-Parmer® HILIC HPLC & UHPLC Columns and Accessories

Designed to aid in the separation and retention of very polar analytes
  • Use to increase sensitivity in MS analysis
  • Provides alternate selectivity to that achieved with reversed phase C18
  • Reduced extraction and dry down times
Hydrophilic Interaction Liquid Chromatography (HILIC) columns are ideal for the retention and separation of polar to highly polar compounds. The partitioning, ion-exchange, and hydrogen bonding that occur on a HILIC stationary phase assist with extended retention. Normally water is used in low concentration as the strong solvent to elute the compounds.

Columns come in 316L stainless steel (SS) tubing hardware. A SS female end fitting with a SS and PEEK frit system keeps the stationary phase in place and packed bed from disturbance. The SS end fitting accepts a male 10-32 threaded nut with standard 1/16" OD tubing.

Use the guard cartridges to maintain chromatographic integrity. They ensure erroneous materials are kept out of the more important and expensive analytical columns, leading to more accurate results. Simply match the sizes to select the correct guard cartridge for your column; guard cartridge holder 16470-89 is required to use the guard cartridges. In-line filters are available for your UPHLC and HPLC columns—order separately.
$338.00 - $664.00USD / Each

21 variations of this product are available.

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Column Inside Diameter (ID) (mm) Column Particle Size (µm) Description
Availability Pricing
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4.6 5 HILIC HPLC Column, 5 µm, 250 mm L x 4.6 mm ID; 1/EA
$600.00USD / Each
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4.6 5 HILIC HPLC Column, 5 µm, 150 mm L x 4.6 mm ID; 1/EA
$578.00USD / Each
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4.6 5 HILIC HPLC Column, 5 µm, 100 mm L x 4.6 mm ID; 1/EA
$567.00USD / Each
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2.1 5 HILIC HPLC Column, 5 µm, 50 mm L x 2.1 mm ID; 1/EA
$513.00USD / Each
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4.6 3 HILIC HPLC Column, 3 µm, 150 mm L x 4.6 mm ID; 1/EA
$632.00USD / Each
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4.6 3 HILIC HPLC Column, 3 µm, 100 mm L x 4.6 mm ID; 1/EA
$621.00USD / Each
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2.1 3 HILIC HPLC Column, 3 µm, 150 mm L x 2.1 mm ID; 1/EA
$589.00USD / Each
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2.1 3 HILIC HPLC Column, 3 µm, 100 mm L x 2.1 mm ID; 1/EA
$578.00USD / Each
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2.1 3 HILIC HPLC Column, 3 µm, 50 mm L x 2.1 mm ID; 1/EA
$567.00USD / Each
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4.6 1.7 HILIC UHPLC Column, 1.7 µm, 50 mm L x 4.6 mm ID; 1/EA
$664.00USD / Each
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2.1 1.7 HILIC UHPLC Column, 1.7 µm, 150 mm L x 2.1 mm ID; 1/EA
$631.00USD / Each
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2.1 1.7 HILIC UHPLC Column, 1.7 µm, 100 mm L x 2.1 mm ID; 1/EA
$621.00USD / Each
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2.1 1.7 HILIC UHPLC Column, 1.7 µm, 50 mm L x 2.1 mm ID; 1/EA
$610.00USD / Each
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4.6 5 HILIC Guard Cartridges, 5 µm, 10 mm L x 4.6 mm ID; 2/PK
$338.00USD / Pkg of 2
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4.6 5 HILIC Guard Cartridges, 5 µm, 10 mm L x 4.6 mm ID; 4/PK
$608.00USD / Pkg of 4
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2.1 5 HILIC Guard Cartridges, 5 µm, 10 mm L x 2.1 mm ID; 2/PK
$338.00USD / Pkg of 2
COMPARE
2.1 5 HILIC Guard Cartridges, 5 µm, 10 mm L x 2.1 mm ID; 4/PK
$608.00USD / Pkg of 4
COMPARE
4.6 3 HILIC Guard Cartridges, 3 µm, 10 mm L x 4.6 mm ID; 2/PK
$338.00USD / Pkg of 2
COMPARE
4.6 3 HILIC Guard Cartridges, 3 µm, 10 mm L x 4.6 mm ID; 4/PK
$608.00USD / Pkg of 4
COMPARE
2.1 3 HILIC Guard Cartridges, 3 µm, 10 mm L x 2.1 mm ID; 2/PK
$338.00USD / Pkg of 2
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