Siloxane Shortage – Alternative Tubing Solutions

As you may be aware, there is currently a global shortage of siloxane that is forcing a limited supply and a rise in silicone prices globally.

The latest information supports a potential multi-year or long-term issue affecting the global supply of silicone raw materials. Unfortunately, we are now seeing an impact to our ability to provide you with silicone tubing in a timely manner and at our current prices.

Cole-Parmer offers a wide range of tubing solutions to meet your needs. All of the formulations listed below are biocompatible USP class VI and FDA 21 CFR 177.2600 certified and have validation documents available. If you are unsure of your next steps or need assistance, please contact our application specialists.

Our Best Tubing for High Purity Applications

Masterflex Puri-Flex Pump Tubing:

  • Beats silicone in key performance tests
  • Always in stock
  • Heat sealable and weldable
  • Low extractables or leachables
  • Low spallation (particle release) to products
  • Low protein binding

For cell harvest and media process systems as well as bioreactor process lines.

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Masterflex translucent peristaltic pump tubing

PURI-FLEX

Premium translucent Masterflex tubing offering much lower spallation and longer pump life than silicone.

Other Great Alternatives to Silicone Tubing:

For buffer and media preparation, single-use assemblies, and aseptic sealing/welding.

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Masterflex opaque peristaltic pump tubing

Pharmed

A popular opaque tubing option in the bioprocess community. Pharmed ™ is nontoxic, nonhemolytic, and heat sealable and weldable.
Buy Pharmed tubing

For manufacture of vaccines and production filtration and fermentation.

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Masterflex opaque peristaltic pump tubing

PHARMAPURE®

The cleanest running formulation we offer, this opaque ultra-low spallation formulation is the optimal choice for aseptic and bioprocesses.
Buy PHARMAPURE tubing

For specialty chemical production/processing and diagnostic testing.

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Masterflex opaque peristaltic pump tubing

CHEM-DURANCE® BIO

When you need chemical and bio-compatibility with extra low spallation, there is no better choice. Opaque tubing.
Buy CHEM-DURANCE BIO tubing

 

Disclaimer: These Masterflex tubing formulations are biocompatible FDA 21 CFR and USP Class VI certified and have validation documents available upon request. Note that these formulations are suggested replacements only; always perform a tubing test before using in your operation.