What is the difference between an analytical balance and a precision balance?

An analytical balance provides readability of 0.1 mg or better, while a precision balance typically reads to 0.001 g or 0.01 g. Analytical balances include draft shields and are designed for highly sensitive measurements. Precision balances handle larger samples and are less affected by environmental conditions.

What readability do I need for my lab application?

You need a readability that is at least one-tenth of your smallest sample weight or required measurement increment. For example, measuring 100 mg samples may require 0.01 mg readability, while gram-level work may only need 0.01 g. Selecting higher readability than necessary increases cost without improving results.

Do lab balances need to be calibrated?

Yes, all lab balances require regular calibration to maintain accuracy. Calibration ensures measurements remain traceable to certified standards. Internal calibration simplifies this process by automating adjustments, while external calibration requires manual verification with certified weights. In regulated environments, calibration records must be documented and retained.

What is the difference between readability and repeatability?

Readability is the smallest increment of weight a balance will display. Repeatability is the degree of agreement between multiple measurements of the same mass, on the same balance, under the same conditions.

What is the best way to clean my balance to ensure accurate readings?

Inspect and clean before each use. A flannel cloth or soft brush works well for dusting and light cleaning. Use a non-abrasive cleaner for light spills, and a dry flannel cloth for glass parts. Set a regular maintenance schedule for deep cleaning to ensure optimal performance and instrument longevity.

Can vibration affect the accuracy of my balance?

Yes — even slight vibration from a heavy footstep can affect accuracy. Place the balance on a sturdy benchtop away from high-traffic areas such as hallways, elevators, stairways, and doors. If that placement is not possible, an anti-vibration table should be considered.

Four Products for Proteomics | from Cole-Parmer Blog

Labs and research facilities rely on instruments and supplies to study an organism’s complete protein profile, referred to as proteomics. Analyzing the functions, structures, and modifications of the protein profile can potentially result in promising new medications.

Key resources for a proteomics lab include:

Vertical electrophoresis systems for characterizing or separating proteins
Dialysis membranes for the gentle separation and purification of solutes
Solid-phase extraction columns for reliable sample preparation
Centrifugal filters for protein concentration and desalting

Preparing proteomic samples may also involve homogenizers, blenders, incubators, centrifuges, microscopes, spectrophotometers, and syringe pumps. Other items to have nearby are:

Dialysis products including dialyzers, spin columns, cassettes, and tubes
Safety equipment such as gloves, safety glasses and goggles, glove boxes, and biosafety equipment to protect your samples
Separation products such as power supplies and multi-well plates

View our full selection of proteomics products.

Four Products for Proteomics

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