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Cole-Parmer® VapLock Closed Systems are ideal safety solutions for scientists, chemical hygienists, and researchers worldwide who work with high performance liquid chromatography (HPLC) and similar liquid-based technologies. Reagent and collection vessels paired with this equipment are often left open or ineffectively sealed during instrument operation, allowing chemical exhaust to be released directly into the laboratory environment through leaks, spills, and improper ventilation. When the fluid pathway is not properly contained, it poses health and safety risks, and—in more recent years—danger of regulatory violation and liability concerns. The products used in VapLock Closed Systems solve this problem by mechanically working together to effectively contain solvent and control the emission of harmful vapors that can be hazardous to both workers and the environment.